The impact of SBF2 on taxane-induced peripheral neuropathy

Shen, Fei; Cantor, Erica L.; Tan, Zhiyong; Bales, Casey L.; Wan, Jun; Wu, Xi; Jiang, Guanglong; Schneider, Bryan P.; Philips, Santosh; Cunningham, Geneva Mari; Gardner, Laura; Liu, Yunlong; Fehrenbacher, Jill

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The impact of SBF2 on taxane-induced peripheral neuropathy

Cunningham, Geneva Mari ; Shen, Fei ; Wu, Xi ; Cantor, Erica L. ; Gardner, Laura ; Philips, Santosh ; Jiang, Guanglong ; Bales, Casey L. ; Tan, Zhiyong ; Liu, Yunlong ; Wan, Jun ; Fehrenbacher, Jill ; Schneider, Bryan P.

URI: https://hdl.handle.net/11243/42
https://doi.org/10.7912/D2/28

Keywords: peripheral neuropathy
SBF2
SET binding factor 2
Cancer Research
Cellular and Molecular Neuroscience

Date: 2021-12-13

Cite As: Geneva M. Cunningham, Fei Shen, Xi Wu, Erica L. Cantor, Laura Gardner, Santosh Philips, Guanglong Jiang, Casey L. Bales, Zhiyong Tan, Yunlong Liu, Jun Wan, Jill Fehrenbacher, & Bryan P. Schneider. (2021). The impact of SBF2 on taxane-induced peripheral neuropathy. [dataset]. IUPUI University Library. https://doi.org/10.7912/D2/28

Published As: Geneva M. Cunningham, Fei Shen, Xi Wu, Erica L. Cantor, Laura Gardner, Santosh Philips, Guanglong Jiang, Casey L. Bales, Zhiyong Tan, Yunlong Liu, Jun Wan, Jill Fehrenbacher, & Bryan P. Schneider. (2021). The impact of SBF2 on taxane-induced peripheral neuropathy. [dataset]. IUPUI University Library. https://doi.org/10.7912/D2/28

Found At: IUPUI University Library

Sponsorship: Vera Bradley Foundation Center for Breast Cancer Research – Monogrammed Medicine

Abstract:

The data represent single and bulk RNA sequencing of human induced pluripotent stem cell-derived sensory neurons (iPSC-dSN). Differential gene expression between the clusters of cells demonstrated the presence of mature sensory neurons in single cell RNA sequencing. Transcriptomic changes were also identified between paclitaxel- and vehicle-treated cells in control and SBF2 knockdown groups of cells.