Data for Artemisinin partial resistance in Ugandan Children with Complicated Malaria

Lima-Cooper, Giselle; Henrici, Ryan; Sutherland, Colin; Dombrowski, Jamille; Namazzi, Ruth; Campino, Susana; Kato, Charles; Conroy, Andrea; Opoka, Robert; Aliwuya, Sadati; John, Chandy; Pratt, Sade

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Data for Artemisinin partial resistance in Ugandan Children with Complicated Malaria

Henrici, Ryan ; Namazzi, Ruth ; Lima-Cooper, Giselle ; Kato, Charles ; Aliwuya, Sadati ; Dombrowski, Jamille ; Pratt, Sade ; Campino, Susana ; Conroy, Andrea ; Sutherland, Colin ; John, Chandy ; Opoka, Robert

URI: https://hdl.handle.net/11243/50
https://doi.org/10.7912/by4b-f498
https://doi.org/10.7912/D2/36

Keywords: malaria
intravenous artesunate
artemisinin
artemisinin partial resistance
propsective study
hospitalization

Date: 2024

Cite As: Henrici, R. C., Namazzi, R., Lima-Cooper, G., Kato, C., Aliwuya, S., Dombrowski, J. G., Pratt, S., Campino, S., Conroy, A. L., Sutherland, C. J., John, C. C., & Opoka, R. O. (2024). Data for Artemisinin Partial Resistance in Uganda Children with Complicated Malaria. [data set]. IUI University Library. https://doi.org/10.7912/by4b-f498

Published As: Henrici, R. C., Namazzi, R., Lima-Cooper, G., Kato, C., Aliwuya, S., Dombrowski, J. G., Pratt, S., Campino, S., Conroy, A. L., Sutherland, C. J., John, C. C., & Opoka, R. O. (2024). Data for Artemisinin Partial Resistance in Uganda Children with Complicated Malaria. [data set]. IUI University Library. https://doi.org/10.7912/by4b-f498

Found At: IUI University Library

Sponsorship: Funding for this study was provided by the Makerere University Research and Innovations Fund and the Riley Children's Foundation.

Abstract:

Intravenous artesunate, a semisynthetic derivative of artemisinin, is the World Health Organization (WHO)–recommended treatment for malaria requiring parenteral treatment. Malaria caused 608 000 deaths in 2022, mostly due to Plasmodium falciparum. Artemisinin partial resistance due to Pfkelch13 variations has been documented in East Africa in uncomplicated malaria2,3 but not in complicated malaria. We assessed artemisinin partial resistance, Pfkelch13 variations, and malaria recrudescence in Ugandan children with complicated malaria.